Compound, or pharmaceutically acceptable salt thereof, having a structure represented by a formula: ** Formula ** wherein A is CR2 or N； where L is O； where W is CR6 or N； where Z is CR6a or N； provided that only one of W and Z is N； wherein R1 is aryl, heteroaryl, cycloalkyl, or heterocycloalkyl； wherein R1 is substituted with 0-3 of R9； wherein R2 is hydrogen, halogen, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, amino, hydroxyl, alkylamino, dialkylamino, NO2, CN, SO2R8 or COR8； wherein R3 is selected from hydrogen, halogen, C1-C6 alkyl, C1-C6 haloalkyl and CN； wherein R4 is selected from hydrogen, halogen, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy and C1-C6 haloalkoxy, hydroxyl, amino, alkylamino, dialkylamino, CN, SO2R8 and COR8； wherein R5 is selected from hydrogen, halogen, C1-C6 alkyl, C1-C6 haloalkyl, CN, SO2R8 and COR8； wherein R6, when present, is selected from hydrogen, halogen, CN, C3-C4 cycloalkyl, C3-C4 halocycloalkyl, C1-C6 alkyl, and C1-C6 haloalkyl； wherein R6a, when present, is selected from hydrogen, halogen, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy and C1-C6 haloalkoxy； wherein R6b is selected from hydrogen, halogen, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy, and C1-C6 haloalkoxy； wherein R6c is selected from hydrogen, halogen, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy, and C1-C6 haloalkoxy； wherein R8 is C1-C6 alkyl, C1-C6 cycloalkyl, amino, alkylamino, or dialkylamino； and wherein each R9, when present, is independently halogen, C1-C6 alkyl, C1-C6 haloalkyl, C3-C4 cycloalkyl, C3-C4 halocycloalkyl, C1-C6 haloalkoxy, hydroxyl, amino, alkylamino. , dialkylamino, NO2, CN, SO2R8 or COR8.Compuesto, o sal farmacéuticamente aceptable del mismo, que tiene una estructura representada por una fórmula:**Fórmula** en el que A es CR2 o N； en el que L es O； en el que W es CR6 o N； en el que Z es CR6a o N； siempre que sólo uno de W y Z sea N； en el que R1 es arilo, heteroarilo, cicloalquilo o heterocicloalquilo； en el que R1 está sustitui
