Yuki Iwaki,Rajeshri Ganesh Karki,Gary Michael Ksander
申请号:
US13688630
公开号:
US08822534B2
申请日:
2012.11.29
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides a compound of formula I′;or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, B1, X and n are defined herein. The invention also relates a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.