Toshio KAWANAMI;Muneto MOGI;Robert SUN;Yuki IWAKI;Rajeshri Ganesh KARKI;Gary Mark COPPOLA;Gary Michael KSANDER
发明人:
Gary Mark COPPOLA,Yuki IWAKI,Rajeshri Ganesh KARKI,Toshio KAWANAMI,Gary Michael KSANDER,Muneto MOGI,Robert SUN
申请号:
US14306429
公开号:
US20140296240A1
申请日:
2014.06.17
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides a compound of formula I′;or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, B1, X and n are defined herein. The invention also relates a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.