Toshio Kawanami;Muneto Mogi;Robert Sun;Yuki Iwaki;Rajeshri Ganesh Karki;Gary Mark Coppola;Gary Michael Ksander
发明人:
Gary Mark Coppola,Yuki Iwaki,Rajeshri Ganesh Karki,Toshio Kawanami,Gary Michael Ksander,Muneto Mogi,Robert Sun
申请号：
US12788766
公开号：
US08394853B2
申请日:
2010.05.27
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides a compound of formula I′；or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, B1, X and n are defined herein. The invention also relates a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
