您的位置: 首页 > 农业专利 > 详情页

A Method of Preparing Amorphous Solid Dispersion in Submicron Range by Co-Precipitation
专利权人:
HOVIONE INTERNATIONAL LTD
发明人:
Marcio TEMTEM,Ruben PEREIRA,João VICENTE,Filipe GASPAR,Iris DUARTE
申请号:
US15500432
公开号:
US20170209372A1
申请日:
2015.07.31
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention discloses a method for producing amorphous solid dispersions in a nanoparticulate form, through solvent controlled co-precipitation, using microfluidization/microreaction technology to promote high energy mixing/interaction at a micro and/or molecular level between the streams involved in the process. Feed streams, solvent and anti-solvent, are fed to an intensifier pump at individually controlled rates and forced to interact to micro- and/or nano-scale within a microreactor. The present invention also discloses amorphous solid dispersions obtained by the method of the invention as well as pharmaceutical compositions containing the same.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充