A biopsy assembly including a biopsy catheter having a proximal portion and adistalportion, a navigation catheter configured to receive the biopsy catheter forpositioning the biopsycatheter adjacent target tissue, wherein the biopsy catheter is configured tobe received within thenavigation catheter, a coring component, and an anchoring component configuredto anchor thebiopsy catheter to target tissue. The coring component includes a proximalregion and a distalregion, the distal region formed of one or more distally extending blades andthe proximal regionbeing coupled to the distal portion of the biopsy catheter and the one or moreblades areconfigured to penetrate target tissue and sever a tissue sample from thetarget tissue.
