Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
发明人:
Wu Zhong,Meiyan Yang,Wei Gong,Yuli Wang,Chunsheng Gao,Xinbo Zhou,Song Li
申请号:
US16318044
公开号:
US20190336479A1
申请日:
2017.07.04
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to a pharmaceutical composition of Tecovirimat for injection, comprising Tecovirimat as an active ingredient, cyclodextrin and an additive. The present invention also relates to a method for preparing the pharmaceutical composition. The composition improves the solubility of Tecovirimat in water by using cyclodextrin and meglumine in combination, as compared with the solubility of Tecovirimat in water by using cyclodextrin or meglumine alone.