Jaeschke, Georg,Lindemann, Lothar,Ricci, Antonio,Rueher, Daniel,Stadler, Heinz,Vieira, Eric
申请号：
NZ70353713
公开号：
NZ703537A
申请日:
2013.10.15
申请国别(地区):
NZ
年份:
2018
代理人:
摘要：
The present invention relates to ethynyl derivatives of formula I wherein Y is N or CH R1 is fluoro or chloro or to a pharmaceutically acceptable acid addition salt thereof. The compounds of general formula I are metabotropic glutamate receptor antagonists (negative allosteric modulators) for use in the treatment of anxiety and pain, depression, Fragile-X syndrome, autism spectrum disorders, Parkinson’s disease, and gastroesophageal reflux disease (GERD).
