Frank DeRosa,Michael Heartlein,Daniel Crawford,Shrirang Karve
申请号:
US16540791
公开号:
US20200172923A1
申请日:
2019.08.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides, among other things, multimeric coding nucleic acids that exhibit superior stability for in vivo and in vitro use. In some embodiments, a multimeric coding nucleic acid (MCNA) comprises two or more encoding polynucleotides linked via 3′; ends such that the multimeric coding nucleic acid compound comprises two or more 5′; ends.