Frank DeRosa,Michael Heartlein,Daniel Crawford,Shrirang Karve
申请号：
US15482431
公开号：
US20170314041A1
申请日:
2017.04.07
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides, among other things, multimeric coding nucleic acids that exhibit superior stability for in vivo and in vitro use. In some embodiments, a multimeric coding nucleic acid (MCNA) comprises two or more encoding polynucleotides linked via 3′ ends such that the multimeric coding nucleic acid compound comprises two or more 5′ ends.
