Woo Kie MIN,Dong Hoon LEE,Hyeon Jun KIM,Jae Hyuk YANG,Lih WANG,Duk Hyun LEE
申请号：
US15578576
公开号：
US20180154040A1
申请日:
2015.10.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to a scaffold preparation method and a scaffold prepared thereby, and more particularly to a method for preparing a scaffold for promoting bone regeneration, the method comprising physically and chemically attaching collagen and SDF-1 to the scaffold, and to a scaffold prepared thereby. According to the present invention, the surface of a scaffold is treated with 3-APTES so that collagen and SDF-1 can be physically and chemically attached to the scaffold, so that the release rate of SDF-1 on the scaffold will not rapidly change even with the passage of time while integrin will recognize SDF-1 of the scaffold as a suitable extracellular matrix, thereby shortening the time required for restoration of bone defects.
