FEDERALNOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "NAUCHNYJ TSENTR NEVROLOGII" ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK
发明人:
CHERNIKOVA LJUDMILA ALEKSANDROVNA,Черникова Людмила Александровна,CHERVJAKOV ALEKSANDR VLADIMIROVICH,Червяков Александр Владимирович,KREMNEVA ELENA IGOREVNA,Кремнева Елена Игоревна,KONOVALOV RODION NI
申请号：
RU2012141806/14
公开号：
RU0002504329C1
申请日:
2012.10.02
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention relates to medicine neurology and can be used for studying state of zones of sensomotor system activation in the process of motor rehabilitation in patients after impairment of cerebral blood flow in order to carry out correction of rehabilitating procedures. MRT in Tl MPR (Multiplanar reconstruction) mode fMRT with further navigational transcranial magnetic stimulation are performed. FMRT is performed with application of sensomotor passive paradigm (SMPP), imitating support load in the process of walking by means of apparatus "KORVIT". MRT data obtained in TI MPR and fMRT are downloaded into NBS eXimia Nexstim system and individual three-dimensional model of examined patients brain is built with application of identified on fMRT activation zones on it. Real anatomical formations of brain are correlated with data, obtained on MRT in T1 MPR modes, after which EMG-electrodes of eXimia Nexstim system are applied on shin muscles to be examined: m. gastrocnemius, m. soleus, m. tibialis anterior, taking part in the process of walking. To register induced motor responses (IMR) magnetic stimulation of activation obtained on fMRT zones, with determination of IMR, which have amplitude 100-500 mcV, with tension of magnetic field in stimulation point 80-110 V/m, is performed. Point with maximal amplitude of IMR is identified and passive motor threshold is determined in it by minimal intensity of magnetic stimulation, at which IMR with amplitude higher than 50 mcV are registered in more than half of repeated stimuli. Motor representation of muscles by intensity 100% of selected motor threshold is mapped on individual three-dimensional model of brain to localise sensomotor zones of cerebral cortex, responsible for locomotion.EFFECT: method ensures increased accuracy of identifying zones of motor representation in cerebral cortex of muscles, taking part in walking, with building individual map of motor representation of target-muscles in cerebr
