HCV NS-3 Serinproteasehemmere

• 收藏
• 分享

专利权人:

Janssen Sciences Ireland UC;Medivir AB

发明人:

Rosenquist, Åsa,Thorstensson, Fredrik,Johansson, Per-Ola,Kvarnstrom, Ingemar,Ayesa, Susana,Classon, Björn,Rakos, Lazlo,Samuelsson, Bertil

申请号：

NO20063850

公开号：

NO340695B1

申请日:

2006.08.29

申请国别(地区):

NO

年份:

2017

代理人:

摘要：

Peptidomimetic compounds are described which inhibit the NS3 protease of the hepatitis C virus (HCV). The compounds have the formula where the variable definitions are as provided in the specification. The compounds comprise a carbocyclic P2 unit in conjunction with a novel linkage to those portions of the inhibitor more distal to the nominal cleavage site of the native substrate, which linkage reverses the orientation of peptidic bonds on the distal side relative to those proximal to the cleavage site.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/