Cellular markers useful for methods of diagnosing multiple sclerosis (MS), relapse of MS patients and disease progression in MS patients, as well as identifying treatments for and monitoring treatment of patients with multiple sclerosis (MS). Methods of differential diagnosis of patients presenting with clinically isolated syndrome (CIS) suggestive of MS and/or Radiologically Isolated Syndrome (RIS) for presence of MS or relapse of MS, or lack thereof. Methods of treating patients having multiple sclerosis.
