GOLEBIOWSKI, ADAM A.,KORALEWSKI, ROBERT,CZESTKOWSKI, WOJCIECH,MATYSZEWSKI, KRZYSZTOF,OLEJNICZAK, SYLWIA,OLCZAK, JACEK,BECKETT, PAUL R.
申请号:
CA2971395
公开号:
CA2971395A1
申请日:
2015.12.18
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Disclosed are amino triazole compounds substituted by a carboxylate functional group or an bioisosteric polar functional group. Compounds having the carboxylate moiety or carboxylate bioisostere inhibit acidic mammalian chitinase. Also provided are methods of using the compounds to treat asthma reactions caused by allergens.