Substituted amino triazoles useful as acidic mammalian chitinase inhibitors

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专利权人:

Oncoarendi Therapeutics S.A.

发明人:

Golebiowski, Adam A.,Koralewski, Robert,Czestkowski, Wojciech,Matyszewski, Krzysztof,Olejniczak, Sylwia,Olczak, Jacek,Beckett, Paul R.

申请号：

AU2015363761

公开号：

AU2015363761A1

申请日:

2015.12.18

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

Disclosed are amino triazole compounds substituted by a carboxylate functional group or an bioisosteric polar functional group. Compounds having the carboxylate moiety or carboxylate bioisostere inhibit acidic mammalian chitinase. Also provided are methods of using the compounds to treat asthma reactions caused by allergens.

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