Adam Golebiowski,Robert Koralewski,Wojciech J. Czestkowski,Krzysztof Matyszewski,Sylwia Olejniczak,Jacek Olczak,Paul Beckett
申请号:
US14959369
公开号:
US09440953B2
申请日:
2015.12.04
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed are amino triazole compounds substituted by a carboxylate functional group or an bioisosteric polar functional group. Compounds having the carboxylate moiety or carboxylate bioisostere inhibit acidic mammalian chitinase. Also provided are methods of using the compounds to treat asthma reactions caused by allergens.