The disclosure provides a plurality of platinum nanoparticles (Pt NPs) with bacterial toxicity, wherein the Pt NPs have a diameter between 1-3 nm. The disclosure also provides a plurality of platinum nanoparticles (Pt NPs) with bacterial compatibility, wherein the Pt NPs have a diameter between 4-21 nm. The disclosure further provides uses of the two Pt NPs mentioned above.本發明提供一種具有細菌毒性的鉑奈米粒子,其直徑介於1-3 nm。本發明亦提供一種具有細菌相容性的鉑奈米粒子,其直徑介於4-21 nm。本發明另提供上述兩種鉑奈米粒子之用途。