BESWICK, PAUL JOHN,GLEAVE, ROBERT JAMES,HACHISU, SHUJI,VILE, SADIE,BERTHELEME, NICOLAS,WARD, SIMON E
申请号：
ES11738465
公开号：
ES2529233T3
申请日:
2011.07.08
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
A compound of formula (I), or a salt thereof: ** ** Formula wherein A is ** ** Formula R1 is hydrogen, methyl or chlorine R2 is hydrogen, trifluoromethyl, trifluoromethoxy, chlorine or cyano R3 is hydrogen, cyano, trifluoromethyl, trifluoromethoxy, difluoromethoxy, chlorine, bromine, -S-CH3, -S02-C 1-3 alkyl or - SF5 R4 is hydrogen, trifluoromethyl, trifluoromethoxy, chlorine or cyano R6 is hydrogen, methyl or chlorine wherein at least one of R1, R2, R3, R4 or R5 is a group other than hydrogen X is -CH2-, -CH2-CH2- or -CH (CH3) - wherein when R1 is methyl, R6 is hydrogen or chlorine, and when R6 is methyl, R1 is hydrogen or chlorine wherein when R2 is chlorine, R4 is hydrogen, trifluoromethyl, trifluoromethoxy or cyano, and R4 is chloro when R2 is hydrogen, trifluoromethyl, trifluoromethoxy or cyano R6 is hydrogen and R7 is C1-6 alkyl or C3-6 cycloalkyl 0 R6 and R7 together with the nitrogen atom at which they are attached form a saturated ring system B, wherein B a bicyclic ring system condensate is selected from a) a monocyclic 4 heterocidico ring to 7-b) 5 to 10 members c) a monocyclic heterocyclic ring linked by bridges of 4 to 7 members d) a spiro ring system of 7 to 11 membersUn compuesto de fórmula (I), o una sal del mismo:**Fórmula** en donde A es**Fórmula** R1 es hidrógeno, metilo o cloro R2 es hidrógeno, trifluorometilo, trifluorometoxi, cloro o ciano R3 es hidrógeno, ciano, trifluorometilo, trifluorometoxi, difluorometoxi, cloro, bromo, -S-CH3, -S02-alquilo C1_3 o - SF5 R4 es hidrógeno, trifluorometilo, trifluorometoxi, cloro o ciano R6 es hidrógeno, metilo o cloro en el que al menos uno de R1, R2, R3, R4 o R5 es un grupo distinto de hidrógeno X es -CH2-, -CH2-CH2- o -CH(CH3)- en el que cuando R1 es metilo, R6 es hidrógeno o cloro, y cuando R6 es metilo, R1 es hidrógeno o cloro en donde, cuando R2 es cloro, R4 es hidrógeno, trifluorometilo, trifluorometoxi o ciano, y cuando R4 es cloro, R2 es hidrógeno, trifluorometilo, trifluorometoxi o ciano R6 es hidró
