Primiano, Thomas,Bookbinder, Lonnie,Chang, Bey-Dih,Heidel, Jeremy
申请号:
AU2016202538
公开号:
AU2016202538A1
申请日:
2016.04.21
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
#$%^&*AU2016202538A120160512.pdf#####ABSTRACT This invention describes a genetic system for targeting the EV11 gene in mammalian cells. The EV11 gene is an oncogenic transcription factor that, when 5 expressed, accelerates cell division and inhibits death of cells. Nucleotide sequences that block the expression of EV11 and drug delivery systems for them are described. These nucleotide sequences cause a block in cell growth and division and trigger death of mammalian cells, including lung and ovarian cancer cells. 10