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REWIRING ABERRANT CANCER SIGNALING TO A THERAPEUTIC EFFECTOR RESPONSE WITH A SYNTHETIC TWO-COMPONENT SYSTEM
专利权人:
The Board of Trustees of the Leland Stanford Junior University
发明人:
Hokyung Chung,Michael Z. Lin
申请号:
US16400976
公开号:
US20190256833A1
申请日:
2019.05.01
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Compositions and methods for targeted treatment of cancer are disclosed. In particular, the invention relates to methods of targeting anti-cancer therapy to cells exhibiting aberrant signaling associated with cancer pathogenesis by administering synthetic signaling proteins that couple detection of an oncogenic signal to release of therapeutic agents into cancerous cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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