equation (1): (wherein, the R 1 is an acyl group represented by -CO- linear or branched chain acyl group of a saturated or unsaturated 2-24 carbon atoms show .R 2 and R 3 each independently represent hydrogen atom, OH group or an oR 5 group, R 5 is a straight-chain or .R illustrating a hydrocarbon group branched 4 is a hydrogen atom, saturated or unsaturated having 1 to 6 carbon atoms or a saturated 1 to 6 carbon atoms, or a linear or branched unsaturated hydrocarbon group.) acyl dipeptide derivatives or salts thereof represented by has an excellent antimicrobial effect, a composition containing the compound is used excellent feeling.式(1):(式中、R1-CO-で表されるアシル基は炭素原子数2~24の飽和または不飽和の直鎖または分岐鎖のアシル基を示す。R2およびR3はそれぞれ独立に水素原子、OH基またはOR5基を示し、R5は炭素原子数1~6の飽和または不飽和の直鎖または分岐鎖の炭化水素基を示す。R4は水素原子、または炭素原子数1~6の飽和もしくは不飽和の直鎖もしくは分岐鎖の炭化水素基を示す。)で表されるアシルジペプチド誘導体またはその塩は、優れた抗菌効果を有し、当該化合物を含有する組成物は使用感に優れる。