Viral vectors that express viruses or genes that grow in hypoxic cells

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专利权人:

独立行政法人科学技術振興機構

发明人:

高橋 克仁,山村 倫子,井上 正宏

申请号：

JP2009550011

公开号：

JP5186693B2

申请日:

2009.01.13

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

The present invention provides a virus or a viral vector capable of expressing a gene specifically in a cell having replication ability in a hypoxic state such as a cancer stem cell and injuring the cell, and a pharmaceutical composition comprising the same. Specifically, the present invention provides a virus or a viral vector which comprises a gene encoding a fusion protein of an ODD and a protein essentially required for viral proliferation, and a pharmaceutical composition comprising the same.

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中国工程科技知识中心

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