"ANTIBODY, OR ANTIGEN CONNECTION FRAGMENT OF THIS NUCLEIC ACID MOLECLE, VECTOR, CELL EXPRESSING THE ANTIBODY, ISOLATED OR PURIFIED IMMUNOGENIC COMPOSITION, INFECTIOUS REDUCTION, PHARMACEUTICAL COMPOSITION OF THE RISK OF INFECTION BY VIRUS INFLUENCES A, AND, EPITON THAT SPECIFICALLY LINKS TO THE ANTIBODY "

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专利权人:

INSTITUTE FOR RESEARCH IN BIOMEDICINE

发明人:

ANTONIO LANZAVECCHIA

申请号：

BRPI0911699

公开号：

BRPI0911699A2

申请日:

2009.07.27

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

The invention relates to antibodies, and antigen binding fragments thereof, that bind to hemagglutinin and neutralize a group 1 subtype and a group 2 subtype of influenza A virus. The invention also relates to nucleic acids that encode, immortalized B cells and cultured single plasma cells that produce, and to epitopes that bind to such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and epitopes in screening methods as well as in the diagnosis, treatment and prevention of influenza A virus infection.

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中国工程科技知识中心

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