Novel substituted indoloquinoxalines of formula (I R2 (I) Y Wherein R1 ishydrogen or represents one or more similar or different substituents in thepositions 7 to 10 selected from the group halogen, lower alkyl/alkoxy,hydroxy, trifluoromethyl, trichloromethyl, trifluoromethoxy, R2 representssimilar or different C1-C4 alkyl substituents, X is CO or CH2, Y is OH, NH2,NH-(CH2)n-R3 wherein R3 represents lower alkyl, OH, NH2, NHR4 or NR5R6 whereinR4, R5 and R6 independently are lower alkyl or cyclo~alkyl and n is an integerof from 2 to 4, with the provision that when X is CH2, Y is OH or NH-(CH2)n-OH, and pharmacologically acceptable salts thereof are described. Thecompounds are useful as drugs for preventing and/or treating autoimmunediseases.