DERYK T. LOO,PAUL A MOORE,LESLIE S JOHNSON,LING HUANG,FRANCINE ZHIFEN CHEN
申请号：
ZA201206556
公开号：
ZA201206556B
申请日:
2012.08.31
申请国别(地区):
ZA
年份:
2013
代理人:
摘要：
The present invention relates to antibodies and their fragments that are immunoreactive to the mammalian, and more particularly, the human B7-H3 receptor and to uses thereof, particularly in the treatment of cancer and inflammation. The invention thus particularly concerns humanized B7-H3-reactive antibodies and their immunoreactive fragments that are capable of mediating, and more preferably enhancing the activation of the immune system against cancer cells that are associated with a variety of human cancers.
