LOO, Deryk, T.,HUANG, Ling,MOORE, Paul, A.,CHEN, Francine, Zhifen,JOHNSON, Leslie, S.
申请号：
TN2012000437
公开号：
TN2012000437A1
申请日:
2012.09.03
申请国别(地区):
TN
年份:
2014
代理人:
摘要：
The present invention relates to antibodies and their fragments that are immunoreactive to the mammalian, and more particularly, the human B7-H3 receptor and to uses thereof, particularly in the treatment of cancer and inflammation. The invention thus particularly concerns humanized B7-H3- reactive antibodies and their immunoreactive fragments that are capable of mediating, and more preferably enhancing the activation of the immune system against cancer cells that are associated with a variety of human cancers.
