Antimicrobial preservatives to achieve multi-dose formulation using beta-cyclodextrins for liquid dosage forms

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专利权人:

ZOETIS SERVICES LLC

发明人:

申请号：

ARP170102291

公开号：

AR109357A2

申请日:

2017.08.16

申请国别(地区):

AR

年份:

2018

代理人:

摘要：

The present invention is directed to pharmaceutical compositions containing a therapeutically effective amount of an Active Pharmaceutical Ingredient (API), a pharmaceutically acceptable cyclodextrin and a pharmaceutically acceptable preservative. The invention is also directed to pharmaceutical compositions of the compounds of Formula (I) wherein R<2> is selected from the group consisting of methyl, ethyl, isopropyl, sec-butyl and tert-butyl and a pharmaceutically acceptable cyclodextrin and preservative. Formula (I): In particular, the invention is directed to pharmaceutical compositions of the compound of Formula la, and a pharmaceutically acceptable cyclodextrin and a preservative.

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