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Antimicrobial preservatives to achieve multi-dose formulation using beta-cyclodextrins for liquid dosage forms
专利权人:
Roger C. Adami;Julia Ann Wood;Frederick David
发明人:
Roger C. Adami,Frederick David,Julia Ann Wood
申请号:
US10588070
公开号:
US08183230B2
申请日:
2005.01.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to pharmaceutical compositions containing a therapeutically effective amount of an Active Pharmaceutical Ingredient (“API”), a pharmaceutically acceptable cyclodextrin and a pharmaceutically acceptable preservative. The invention is also directed to pharmaceutical compositions of the compounds of Formula (I) wherein R2 is selected from the group consisting of methyl, ethyl, isopropyl, sec-butyl and tert-butyl and a pharmaceutically acceptable cyclodextrin and preservative. Formula (I): In particular, the invention is directed to pharmaceutical compositions of the compound of Formula 1a, and a pharmaceutically acceptable cyclodextrin and a preservative.
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