RÉGULATION PAR EGFR ET PAR2 DE LA PERMÉABILITÉ INTESTINALES

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专利权人:

UNIVERSITY OF MARYLAND, BALTIMORE;GOLDBLUM, SIMEON;UNIVERSITY OF MARYLAND; BALTIMORE

发明人:

FASANO, ALESSIO,LAMMERS, KAREN,SHEA-DONOHUE, TEREZ

申请号：

EP10786502

公开号：

EP2440246A4

申请日:

2010.06.10

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention provides a method of treating an autoimmune disease, comprising the steps of increasing transepithelial electrical resistance leading to decreased cell permeability. Further provided is ajnethod of treating celiac disease in an individual in need of such treatment, comprising the steps of: administering an antibody directed against single chain zonulin thereby inhibiting epidermal growth factor receptor and inhibiting PAR2.

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