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EGFR and PAR2 regulation of intestinal permeability
专利权人:
UNIVERSITY OF MARYLAND; BALTIMORE
发明人:
Fasano, Alessio,Lammers, Karen,Shea-Donohue, Terez,Goldblum, Simeon
申请号:
AU2010259213
公开号:
AU2010259213A1
申请日:
2010.06.10
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention provides a method of treating an autoimmune disease, comprising the steps of increasing transepithelial electrical resistance leading to decreased cell permeability. Further provided is ajnethod of treating celiac disease in an individual in need of such treatment, comprising the steps of: administering an antibody directed against single chain zonulin thereby inhibiting epidermal growth factor receptor and inhibiting PAR.
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