Pharmaceutical combinations comprising an inhibitor of b-raf, an inhibitor of the epidermal growth factor receptor inhibitor and optionally a pi3halpha and use in the treatment of a proliferative disease.

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专利权人:

NOVARTIS AG

发明人:

CAPONIGRO, GIORDANO,STUART, DARRIN,MOUTOUH-DE PARSEVAL, LAURE

申请号：

CL2015000294

公开号：

CL2015000294A1

申请日:

2015.02.06

申请国别(地区):

CL

年份:

2015

代理人:

摘要：

A pharmaceutical combination comprising (a) a B-Raf inhibitor, (b) a EGFR inhibitor and, optionally, (c) a PI3K inhibitor； the uses of such combination in the treatment of proliferative diseases； and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.SE DESCRIBE UNA COMBINACIÓN FARMACÉUTICA, LA CUAL COMPRENDE: A) UN INHIBIDOR DE B-RAF, B) UN INHIBIDOR DEL RECEPTOR DEL FACTOR DE CRECIMIENTO EPIDÉRMICO (EGFR) Y OPCIONALMENTE C) UN INHIBIDOR DE PI3K. ADEMÁS SE DESCRIBE EL USO DE ESTA COMBINACIÓN EN EL TRATAMIENTO DE ENFERMEDADES PROLIFERATIVAS.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/