Herbal composition for side-effect free treatment of depression, comprising herbs or herbal extracts for promoting blood flow and reducing coagulated blood levels, calming, sedation and flow of Qi
A herbal composition (I) comprises herbs (or their extracts) for: (a) promoting blood flow and reducing coagulated blood levels; (b) calming; (c) sedation; and (d) flow of 'Qi'; where (a) is one of 15 specific herbs (e.g. Salvia multiorhiza), (b) is one of 9 specific herbs (e.g. Lilium brownii), (c) is one of 4 specific herbs (e.g. Rehmannia glutinosa) and (d) is one of 20 specific herbs (e.g. Citrus cinensis). A herbal composition (I) comprises herbs (or their extracts) for: (a) promoting blood flow and reducing coagulated blood levels; (b) calming; (c) sedation; and (d) flow of 'Qi'. Herb (a) is Salvia multiorhiza, Lablab pruprueus, Dendranthema x grandiflorum, Cyperus rotundus, Prunus persica, Prunus davidiana, Paeonia sufruticosa, Senna tora, Tribulus terrestris, Paeonia lactiflora, Crocus sativus, Andrographus paniculata, Ligusticum chuanxiong, Gardenia jasminoides or Cryptotaenia japonica. Herb (b) is Lilium brownii, Ziziphus jujuba, Polygala tenuifolia, Atractylodes macrocephala, Triticum aestivum, Acorus calamus, Anemarrhena asphodeloides, Phyllostachys nigra or Ocimum basilicum. Herb (c) is Rehmannia glutinosa, Gentiara triflora, Gentiann scabra or Schisandra chinensis. Herb (d) is Citrus cinensis, Citrus aurantium, Citrus reticulata, Perillas frutescens, Centella asiatica, Lingusticum sinsense, Angelica sinensis, Curcuma longa, Glycyrrhizia uralensis, Lindera strychnifolia, Gastrodia elata, Saussurea costus, Sparganium stoliniferum, Foeniculum vulgare, Angelica pubescens, Arisaemia amurense, Acorus gramineus, Anemone altaica, Gentiana macrophylla or Gentiana dahuria. - ACTIVITY : Antidepressant; Tranquilizer. In a force swimming test for antidepressant activity in mice, the immobility time for mice treated orally with 6000 mg/kg of a 1:1:1:1 mixture of dried aqueous extracts of Salvia multiorhiza, Lilium brownii, Rehmannia glutinosa and Citrus cinensis was 114 seconds, compared with 104 seconds for mice treated orally with 10 mg/kg of imipramine and 180 seconds for vehicle-only controls. - MECHANISM OF ACTION : None given in the source material.
