The treatment planning engine empowers radiation treatment decision makers, such as a clinician, to efficiently identify optimal radiation treatment results for a given patient. Specifically, the treatment planning engine may identify prior patients associated with previously-administered treatment plans and treatment results, wherein the identified prior patients are similar to a current patient who is to receive radiation treatment. The treatment planning engine generates a set of treatment results for the current patient treatment based on the identified prior patient treatment results. A user interface displays the generated set of treatment results. The clinician is able to input specific criteria, such as features of the patients medical history, into the user interface to filter and modify the displayed set of treatment results based on a similarity between the medical history of the prior patients and the current patient.