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DEIMMUNIZED SERUM-BINDING DOMAINS AND THEIR USE FOR EXTENDING SERUM HALF-LIFE
专利权人:
发明人:
申请号:
HK14103664.3
公开号:
HK1190341B
申请日:
2014.04.16
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
The present invention is directed to a polypeptide (for example, an antigen-binding molecule) that comprises a polypeptide portion of a deimmunized serum-binding protein capable of binding to said serum protein. The presence of the serum-binding protein extends the serum half-life of the polypeptide, relative to the serum half-life of the polypeptide if lacking the polypeptide portion of the deimmunized serum-binding protein. The invention also pertains to methods and uses that employ such molecules.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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