SHUTTLEWORTH, STEPHEN JOSEPH,CECIL, ALEXANDER RICHARD LIAM,HILL, THOMAS JAMES,SILVA, FRANCK ALEXANDRE
申请号：
PL10747483
公开号：
PL2467387T3
申请日:
2010.08.19
申请国别(地区):
PL
年份:
2015
代理人:
摘要：
Compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein: W is O, N&mdash；H, N-(C1-C10 alkyl) or S； each X is independently CH or N； R1 is a 5 to 7-membered saturated or unsaturated, optionally substituted heterocycle containing at least 1 heteroatom selected from N or O； R2 is (LQ)mY； and each R3 is independently H, C1-C10 alkyl, aryl or heteroaryl, are surprisingly found to be inhibitors of PI3K-p110&delta；, and therefore have utility in therapy.
