Wake Forest University Health Sciences;UAB Research Foundation
发明人:
LOWTHER, W. Todd,HOLMES, Ross P.,YOHANNES, Daniel
申请号:
EP16873725
公开号:
EP3386949A4
申请日:
2016.12.07
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
Provided herein are compounds of Formula I and Formula II, and compositions comprising the same, as well as methods of use thereof for treating kidney stones (e.g., inhibiting the formation of oxalate kidney stones; treating primary hyperoxaluria), inhibiting the production of glyoxylate and/or oxalate, and/or inhibiting glycolate oxidase (GO).