Wake Forest University Health Sciences;UAB Research Foundation
发明人:
W. Todd Lowther,Ross P. Holmes,Daniel Yohannes
申请号:
US15781571
公开号:
US20200262794A1
申请日:
2016.12.07
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are compounds of Formula I and Formula II, and compositions comprising the same, as well as methods of use thereof for treating kidney stones (e.g., inhibiting the formation of oxalate kidney stones; treating primary hyperoxaluria), inhibiting the production of glyoxylate and/or oxalate, and/or inhibiting glycolate oxidase (GO).