Augusta University Research Institute;The Regents of the University of California
发明人:
Weimbs Thomas,Jacob Torres,Muthusamy Thangaraju
申请号：
US16819079
公开号：
US20200289444A1
申请日:
2020.03.14
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Compositions and methods for supporting health, especially renal health, comprising ketonic agents that recapitulate beneficial effects of ketosis by exogenously administered agents. The agents include BHB, analogs thereof, and GPR109A agonists. The agents may further include crystal precipitation inhibitors which synergistically improve treatment of certain renal conditions. The agents may be used in dietary supplements and therapeutic compositions for the treatment of cystic kidney diseases such as polycystic kidney disease, ciliopathies, and other conditions.
