Frame rate and/or line density are controlled in contrast agent medical diagnostic ultrasound imaging. The number of lines scanned per second (e.g., frame rate and/or line density) is set based on the differences in contrast agent response. Where the contrast agent response is changing rapidly, more frequent scanning and/or denser scanning is performed. Where the contrast agent response is not changing or changing slowly, less frequent scanning and/or less dense scanning is performed. By linking the number of scan lines per second of the scanning adaptively with the contrast agent response, the destruction of contrast agents may be reduced while providing information when needed for diagnosis.
