In contrast agent imaging, a beamformer and transducer scan a region of a patient having contrast agents. A detector detects the contrast agents with at least two different contrast agent imaging techniques from ultrasound data resulting from the scanning. A processor compares responses of the contrast agents detected between the at least two different contrast agent imaging techniques and selects a relative contribution of the at least two different contrast agent imaging techniques. The selection is based on the comparing. Contrast agent imaging of the patient is performed using at least one of the contrast agent imaging techniques. The performance is based on the selected relative contribution.