The Board of Trustees of the Leland Stanford Junior University
发明人:
Liu, Jie,Weissman, Irving L.,Majeti, Ravindra
申请号：
AU2018204448
公开号：
AU2018204448A1
申请日:
2018.06.20
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018204448A120180712.pdf#####ABSTRACT Humanized or chimeric anti-CD47 monoclonal antibodies are provided. The antibodies bind to and neutralize human CD47, and find use in various therapeutic methods. Preferred are non-activating antibodies. The invention includes isolated antibodies and derivatives and fragments thereof, pharmaceutical formulations comprising one or more of the humanized or chimeric anti-CD47 monoclonal antibodies； and cell lines that produce these monoclonal antibodies. Also provided are amino acid sequences of the antibodies.
