Disclosed are an uplink transmission process number indication method and a related device. The method comprises: a network device receiving an initial transmission packet, and acquiring hybrid automatic repeat request process number association information about the initial transmission packet; and according to a pre-set set of mapping relationships between the hybrid automatic repeat request process number association information and a hybrid automatic repeat request process number, the network device determining the hybrid automatic repeat request process number corresponding to the acquired hybrid automatic repeat request process number association information. According to the embodiments of the invention, a user equipment delivers a hybrid automatic repeat request process number to a network device can be realized.