N2, N4-bis (4- (piperazin-1-yl) phenyl) pyrimidine-2,4-diamine derivative or a pharmaceutically acceptable salt thereof, and cancer containing this derivative or salt as an active ingredient Composition for treating农业专利-农业专业知识服务系统

发明人:: リ，クァンホ,キム，ヒョンレ,パク，チフン,リ，チョンオク,リ，ジョンコク,ジュン，ヒジュン,チョ，ソンヨン,チェ，チョンハク,チョイ，サンウン,ハ，チェトゥ,リ,クァンホ,キム,ヒョンレ,パク,チフン,リ,チョンオク,リ,ジョンコク,ジュン,ヒジュン,チョ,ソンヨン,チェ,チョンハク,チョイ,サンウン,ハ,チェトゥ

摘要：: The present invention relates to a N2,N4-bis(4-(piperazine-1-yl)phenyl)pirimidine-2,4-diamine derivative or a pharmaceutically acceptable salt thereof, and to a composition containing same as an active ingredient for preventing or treating cancer. Since the compound according to the present invention has good effects in inhibiting the activities of anaplastic lymphoma kinase (ALK) and activated Cdc42-associated kinase (ACK1), the compound can have improved therapeutic effects against cancer cells having ALK fusion proteins such as EML4-ALK and NPM-ALK and is expected to be effective in preventing the recurrence of cancer. Therefore, the compound can be effectively used as a composition for preventing or treating cancer.