Rui ZHANG,Mark MACIELAG,Martin A. CASE,Yue- Mei ZHANG,Mark WALL,Raymond, J. PATCH
申请号:
MX2019004952
公开号:
MX2019004952A
申请日:
2017.10.26
申请国别(地区):
MX
年份:
2019
代理人:
摘要:
The present invention comprises compounds of Formula I wherein: Z4, Z7, Z9, Z11, Z22, Z23, Z26, Z30, Z34, Z35, p, m, n, q, and BRIDGE are defined in the specification. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel compounds are useful for preventing, treating or ameliorating diseases and disorders, such as obesity, type 2 diabetes, the metabolic syndrome, insulin resistance, and dyslipidemia, among others.La presente invencion comprende compuestos de Formula I. (ver fórmula) Formula I en donde: Z4, Z7, Z9, Z11, Z22, Z23, Z26, Z30, Z34, Z35, p, m, n, q, y PUENTE se definen en la especificacion; la invencion tambien se relaciona con composiciones farmaceuticas y a metodos para usarlas; los compuestos novedosos son utiles para prevenir, tratar o mejorar enfermedades y trastornos, tales como obesidad, diabetes tipo 2, sindrome metabolico, resistencia a la insulina y dislipidemia, entre otros.