COMPOSITIONS ET METHODES PERMETTANT DE STABILISER LA TRANSTHYRETINE ET D'INHIBER UN MAUVAIS REPLIEMENT DE LA TRANSTHYRETINE

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专利权人:

THE SCRIPPS RESEARCH INSTITUTE

发明人:

KELLY, JEFFERY W.,SEKIJIMA, YOSHIKI,POWERS, EVAN T.,RAZAVI, HOSSEIN

申请号：

CA2800237

公开号：

CA2800237C

申请日:

2003.12.19

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods, screening methods, as well as specific transthyretin stabilizing compounds are disclosed.

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中国工程科技知识中心

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http://www.ckcest.cn/home/