SCRIPPS RESEARCH INST;THE SCRIPPS RESEARCH INSTITUTE
发明人:
申请号：
EP08014241.7
公开号：
EP1988397B8
申请日:
2003.12.19
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods, screening methods, as well as specific transthyretin stabilizing compounds are disclosed.
