Methods for determining whether a compound alters the amount of at least oneαβ(X-41) peptide and the amount of either totalαβor at least oneαβ(X-40) peptide produced by a non-human mammal
ELAN PHARMACEUTICALS, INC.;BRIGHAM AND WOMEN'S HOSPITAL
发明人:
CITRON MARTIN,SELKOE DENNIS J.,SEUBERT PETER A.,SCHENK DALE B.
申请号：
US20020335035
公开号：
US7993627(B2)
申请日:
2002.12.30
申请国别(地区):
美国
年份:
2011
代理人:
摘要：
This invention provides methods of screening compounds for their ability to alter the production of A&bgr;(x≧41) alone or in combination with A&bgr;(x≦̸40). The methods involve administering compounds to cells, specifically measuring the amounts of A&bgr;(x≦̸40) and A&bgr;(x≧41) produced by the cells, and comparing these amounts to that produced by the cells without administration of the compounds.
