PENTIKIS, HELEN S.,PALLING, DAVID,BRAUN, CAROL J. (DECEASED),HOLL, RICHARD
申请号：
CA3046521
公开号：
CA3046521A1
申请日:
2019.06.13
申请国别(地区):
CA
年份:
2020
代理人:
摘要：
Method of treating bacterial vaginosis in a subject in need thereof involvingadministering to the subject a therapeutically effective amount of secnidazolein a microgranuleformulation, wherein the microgranule formulation comprises a plurality ofmicrogranuleshaving a volume-weighted particle size distribution within a microgranulepopulation, whereinthe volume-weighted particle size distribution as measured from arepresentative sample of themicrogranule population comprises (a) 10% of the microgranule populationhaving avolume-weighted particle size about no less than 470 micrometers； (b) 50% ofthe microgranulepopulation having a volume-weighted particle size between about no less than640 micrometersand about no more than 810 micrometers； (c) 90% of the microgranule populationhaving avolume-weighted particle size about no more than 1170 micrometers； or (d) acombinationthereof, which can include some or all of (a) through (c) above.
