Siu Tim Cheung,Sheung-Tat Fan,Phyllis Fung Yi Cheung
申请号:
US14292045
公开号:
US20140356321A1
申请日:
2014.05.30
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Granulin-epithelin precursor (GEP), a pluripotent growth factor, is a hepatic oncofetal protein defining a cancer stem cell (CSC) population in liver cancer. The present invention provides the use of GEP inhibitors (including anti-GEP antibody) for inhibiting immune evasion by liver cancer cells and for eliminating liver cancer stem cells.